Microbiolance

The importance of microbiome analysis

The bacteria in the gut flora interact in complex ways with the human body. They are responsible for the production of essential vitamins and neurotransmitters for many organisms.
Changes in the composition of the normal gut flora can have pathological effects on other organ systems, such as the central nervous system.
Research on the microbiome has been made possible by the development of Next-Generation Sequencing (NGS) techniques, which allow the diversity and distribution of the bacterial communities that make up the gut flora to be studied.

Aim of the development

The aim of our development was the implementation of an IT system for the automated analysis of the correlation between gut flora composition and various diseases, based on bioinformatics and machine learning techniques.

End-to-end microbiome analysis in a user-friendly manner

Whom does Microbiolance help, and how?

Analysis of correlations between cohort-based microbiome and clinical data profiles using AI methods:

Functional Value:
- Introduction of a new disease model: Identification of microbiome markers through the analysis of correlations between cohort-based microbiome and clinical data profiles.
Business Value:
- Supporting the development of new diagnostic and therapeutic opportunities.
Potential Partners:
- Health research institutes
- Clinics - Entities involved in therapy research
- Pharmaceutical companies - R&D

Diagnostics and personalized therapy support based on biomarkers derived from correlations between clinical and microbiome profiles

Functional Value:
- Analysis of correlations between clinical data profiles and microbiome patterns.
- Supporting disease diagnostics and therapy selection decisions.
- Therapy effectiveness analysis by tracking changes in observed gut flora patterns.
- Monitoring the microbiome profiles of patients with clinical histories.
- Comparing microbiome profiles with results in scientific databases using LLM-based AI analyses.
Business Value:
- Significant improvement in diagnostics, therapy selection, and therapy effectiveness based on microbiome-clinical data correlation biomarkers.
- Reduced therapy costs due to shorter therapeutic pathways.
- Disease relapse prediction through monitoring clinical history and microbiome profiles.
- Reporting microbiome profile correlations with specific disease models according to current scientific publications.
Potential Partners:
- Private and public healthcare providers, clinics.

Microbiome profile analysis service for residential and clinical use

Functional Value:
- Reports on microbiome profiles based on bioinformatic processing – bacterial species composition, enrichments, metabolite profiles.
- Comparing microbiome profiles with results in scientific databases using LLM-based AI analyses.
- "Raw" result files from microbiome analysis reports.
Business Value:
- Providing a comprehensive view of the health-related implications of a given profile through reports on bacterial species and metabolite profile deformities based on analysis results from scientific databases.
- Raw result files from microbiome analysis enable further bioinformatic processing, offering flexibility in utilizing sample processing and experimental infrastructure.
Potential Partners:
- Private individuals seeking general microbiome analysis through the system.
- Private and public healthcare providers, clinics.
- Health research institutes.

Support for microbiome analysis laboratory services (LIMS-like functionality)

Functional Value:
- Flexible support for laboratory workflows.
- Bioinformatics processing workflow (processing without requiring specific bioinformatics expertise).
- Offers broader functionality than market competitors.
Business Value:
- Savings on field experts with flexible laboratory workflow management and partial replacement of bioinformatics specialists.
Potential Partners:
- Laboratories: Primarily small to medium-sized biotech entities and laboratories where laboratory process management tasks are unresolved or bioinformatics capacity is limited.

Microbiolance